News11/30/2018
Can Maternal RSV Vaccination Prevent Recurrent Childhood Wheezing?

Early RSV illness is associated with wheeze-associated disorders in childhood. Candidate respiratory syncytial virus (RSV) vaccines may prevent acute RSV illness in infants. In a recent study, researchers investigated the feasibility of maternal RSV vaccine trials to demonstrate reductions in recurrent childhood wheezing in general pediatric populations.  The researchers (including CIR Director Dr. Ruth Karron) was made up of pediatricians, immunologists, vaccinologists, biostatisticians, asthma and other experts to evaluate the likelihood of this type of analysis.  They found that in order to effectively evaluate reductions in recurrent childhood wheezing, the sample sizes would have to be extremely large, making the feasibility of such analysis unlikely.  Read more…