Our Vaccine Research
We test investigational vaccines, virus strains to use in future vaccines and conduct surviellance studies.
![CIR Logo with gradient CIR Logo with gradient](/sites/default/files/styles/rich_text_full_size/public/2023-09/cirlogo300250pxgradient.png?h=57024e64&itok=7w5HPuMF)
CIR faculty are experts in the conduct of clinical trials to evaluate investigational vaccines and generate knowledge about the behavior of pathogens. They conduct early-phase trials to evaluate the safety, immunogenicity, and efficacy of investigational vaccines. Our challenge studies (conducted with adult participants) help characterize the virulence of wild-type viruses and determine the efficacy of vaccines and antiviral agents. We also conduct surveillance for respiratory viruses in pediatric and adult populations.
Explore our vaccine research
![Pediatric Research Pediatric Research](/sites/default/files/styles/tile/public/2023-09/4.png?h=2a479378&itok=YEuC5u-c)
Pediatric Research
The RSVPed team conducts investigational vaccine trials in infants and children and surveillance of respiratory viruses.
![Mucosal Research Mucosal Research](/sites/default/files/styles/tile/public/2023-09/1.png?h=2a479378&itok=6hem2u2d)
Mucosal Research
Mucosal Vaccines and Challenge (MVAC) team conducts investigational vaccine studies for ETEC, Shigella, Cholera, Campy, Ebola, and Influenza as well as challenge studies.
![Flavivirus Research Flavivirus Research](/sites/default/files/styles/tile/public/2023-09/3.png?h=2a479378&itok=NCPEpCVW)
Flavivirus Research
The Flavivirus Immunization Research and Education (FIRE) team conducts investigational vaccine studies for diseases like Dengue Fever, Zika and West Nile.
![COVID19 Research COVID19 Research](/sites/default/files/styles/tile/public/2023-09/2.png?h=2a479378&itok=w2Nl5Tk_)
COVID-19 Research
During the race to delevlop safe and effective COVID-19 vaccines, the RSVPed, FIRE and MVAC teams participated in the evaluation of several COVID-19 vaccine candidates, including Pfizer, Astra Zeneca.