CIR Vaccine Trials – Currently Enrolling

Project SAVE (Support a Vaccine Effort) is the adult recruitment program at the Center for Immunization Research.  The program is used to screen adult potential study participants to help determine their eligibility for specific clinical vaccine studies at the CIR.  Check below for studies that are currently enrolling.

Inpatient

Shigella Inpatient Study (CIR 337)

The purpose of this study is to evaluate the cross-species protection conferred by a re-challenge with a Shigella species of a different serotype.  The study (is):

  • enrolling 18-50 year olds
  • includes 1 or 2 ten day inpatient stays* (about 3-4 months apart)
  • 4-5 outpatient visits after each inpatient stay
  • Pays $2680 for one admission
  • Pays $5170 for two admissions

*not all subjects will be selected to return for admission 2

Complete the CIR Contact Form

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Outpatient

Dose Study to Protect Against Dengue Virus (CIR 332)

The purpose of this study is to evaluate the safety and efficacy of repeated oral doses to protect against exposure to dengue virus.  The study (is):

  • 3 months long
  • 2-3 screening visits
  • 29 consecutive daily visits for oral dosing of medication
  • 2 two-night inpatient stays
  • 1 Dengue challenge visit
  • 8 follow up visits
  • pays up to $4125 for completion of all study procedures

Complete the CIR Contact Form

More about Dengue Virus

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Yellow Fever Vaccine Study (CIR 333)

The purpose of this study is to demonstrate that a new (investigational) yellow fever vaccine is as safe and protective against yellow fever infection as the currently licensed yellow fever vaccine.  The study (is):

  • enrolling 18-60 year olds
  • includes 1 vaccination day visit
  • includes 9-10 follow up visits over 5 years
  • Pays $870-950 depending on visits completed

Complete the CIR Contact Form

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Zika Vaccine Outpatient Study (CIR 318)

The purpose of this study is to evaluate the safety, reactogenicity, and immunogenicity of a single dose of the live attenuated rZIKV/D430-713 vaccine. The study (is):

  • 6 months long
  • enrolling 18-50 year olds
  • includes 2-3 screening visits, 1 vaccine visit, 13 follow up visits with most occurring the first 3 weeks after enrollment
  • pays up to $1520 for completion of all study procedures

Complete the CIR Contact Form

More about  Zika Virus

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