CIR Vaccine Trials – Currently Enrolling

Project SAVE (Support a Vaccine Effort) is the adult recruitment program at the Center for Immunization Research.  The program is used to screen adult potential study participants to help determine their eligibility for specific clinical vaccine studies at the CIR.  Check below for studies that are currently enrolling.

Inpatient

Zika Vaccine Inpatient Study (CIR 316)

The purpose of this study is to learn about the clinical presentation and duration of shedding of the Zika virus in healthy adults.  The study is:

  • 6 months long
  • enrolling FEMALES ONLY 18-40 years old
  • includes 2-3 screening visits, one 16 day inpatient stay and 11 outpatient follow up visits
  • pays up to $5525 for completion of all study procedures

Complete the Pre-Screening Survey to see if you qualify for an in-person screening visit

Complete the CIR Contact Form to be contacted by a CIR staff member

More about  Zika Virus

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Shigella Inpatient Study (CIR 337)

The purpose of this study is to evaluate the cross-species protection conferred by a re-challenge with a Shigella species of a different serotype.  The study (is):

  • enrolling 18-50 year olds
  • includes 1 or 2 ten day inpatient stays* (about 3-4 months apart)
  • 4-5 outpatient visits after each inpatient stay
  • Pays $4950 for one admission
  • Pays $9100 for two admissions

*not all subjects will be selected to return for second admission

Complete the CIR Contact Form or the Pre-Screening Survey

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Outpatient

Lyme Disease Vaccine Study

The main purpose of this study is to determine the safety and immune response of the study vaccine to see if it may protect people against an infectious disease called Lyme borreliosis, also known as Lyme disease.  The study (is):

  • enrolling people 5 years old and older
  • 2 1/2 years long
  • includes 1 screening visit (combined with first vaccination day), 4 vaccination day visit(s), 3 follow up visits and 1 telephone visit
  • pays up to $1031.25

Call us at 410-955-7283 to learn more or complete the Pre-Screening Survey

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COVID/Flu Vaccine Study (CIR 348)

The purpose of this study is to test the safety of receiving a quadrivalent inactivated influenza (flu) vaccine and an mRNA COVID-19 vaccine on the same day or two weeks apart. The study (is):

  • enrolling people 12 and older
  • 4 months long
  • includes 1 phone screening, 3 vaccination day visits, 2 in-person follow-up visits and 4 phone follow-up visits.
  • pays up to $375

Complete the CIR Contact Form 

More about Flu

More about COVID

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Shingrix and Flu Vaccine Study (CIR 345)

This research study aims to compare the safety of administering Shingrix (shingles vaccine) at the same time as FLUAD or Fluzone High-Dose influenza vaccines in older people.  The study (is):

  • enrolling people 65 years old and older
  • 3.5 months long
  • includes 4 clinic visits and 5 phone calls
  • pays up to $325
  • offers Shingriz and Flu vaccines free of charge for people who are enrolled

Complete the CIR Contact Form 

More about Flu

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Dose Study to Protect Against Dengue Virus (CIR 332)

The purpose of this study is to evaluate the safety and efficacy of repeated oral doses to protect against exposure to dengue virus.  The study (is):

  • enrolling people 18-55 years old
  • 3 months long
  • 2-3 screening visits
  • visits every other day for one month
  • 1 two-night inpatient stay
  • 1 Dengue challenge visit
  • 8 follow up visits
  • pays up to $4165 for completion of all study procedures

Complete the Pre-Screening Survey to see if you qualify for an in-person screening visit

Complete the CIR Contact Form to be contacted by a CIR staff member

More about Dengue Virus

Learn More
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